Antedotum: CBD is good. Spread Good.

Antedotum draws on the proven power of 100% pure, organic CBD to transform your skin. We believe CBD is a supernova plant extract that is one of the most healing and therapeutic substances available for skin health. We pride ourselves in crafting the world’s most effective topical CBD and combining it with other scientifically-proven, best-in-breed ingredients to deliver products that are clean, safe, plant-powered and genuinely, transformative.

CBD is good. Spread Good.


You’ll find us in Nirvana, nestled in the Rocky Mountains of Aspen, the beacon to America’s West.  We are surrounded by unparalleled scenery and untamed wilderness. We love the pristine terrain of alpine lakes, waterfalls and wildflowers, the unhurried pace, the magical vibe. This wild place inspires us to bring you the cleanest, most pure products from the American birthplace of CBD.

Purity. Responsibly Sourced.

Purity is next to goodness and is one of Antedotum’s guiding principles. This all starts with the lifecycle of our plants. Grown in rich, sustainable soil, which functions as a vital, living ecosystem, ensures that our hemp is healthy, thriving, and full of active plant compounds. Rigorous purity testing and official organic certification guarantees that you will not find any solvents, pesticides, herbicides or heavy metals — only the purest and cleanest hemp extract is used in Antedotum’s 500MG CBD Complex.


While it is paramount to certify the purity of our products, their potency and strength play an equally critical role. Our 500MG ANTEDOTUM CBD COMPLEX, extracted from the cleanest flowers and leaves of our organic hemp plants, ensures that we can craft the world’s most effective topical CBD. This level is exceptionally high in full spectrum cannabinoids, including both CBD and CBG, offering potent anti-inflammatory, anti-oxidant benefits to soothe irritation, reduce redness, control oil and protect against cell degradation because of the neuro-regenerative properties. We believe in utilizing full-spectrum CBD, allowing all of the hemp plant’s compounds to interact, creating the “entourage effect,” impacting and boosting the performance of our complex.

Research + Science

Antedotum Chief Medical Advisor, Dr. Shawn Demehri, M.D., Ph.D.

At Antedotum, it’s important that all we do be supported by clinical research and scientific evidence. Our Chief Medical Officer, Dr. Shawn Dehehri of Harvard Medical School and Massachusetts General Hospital, helps us achieve that goal.

While we believe wholeheartedly in the undeniable benefits of CBD, we recognize that it is an emerging science for skin health and overall wellness, and want our customers to feel safe in their choice and know that we take our efficacy and claims very seriously.

As a physician-scientist in dermatology, Dr. Shawn’s research areas include molecular/cellular biology of the skin, stem cells, epigenetics, UV protection, inflammation, pigmentation, among others and now, with Antedotum, he applies his decades of skin research experience to the field of CBD.

Through our research we concluded that high potency formulas with concentrated, pure, whole-plant CBD actives have, without question, the greatest effect on the skin.  This is why we developed our 500MG ANTEDOTUM CBD COMPLEX, one of the highest concentrations available in skincare, to effectively correct the signs of aging, optimally protect skin health and also prevent future damage.

Shawn Demehri, M.D., Ph.D.

Certified, American Board of Dermatology
Assistant Professor
Director, High Risk Skin Cancer Clinics

Associate Member, Broad Institute

Center for Cancer Immunology
Cutaneous Biology Research Center

Department of Dermatology and Massachusetts General Hospital Cancer Center
Massachusetts General Hospital
Harvard Medical School

Dr. Shawn is a recipient of American Academy of Dermatology Young Investigator Award and Burroughs Wellcome Fund Career Award for Medical Scientists and NIH Director's Early Independence Award.


Our team is full of gratitude for the many opportunities we have been given.  We believe people thrive within a company culture that demonstrates thankfulness and prizes humility, so for us, giving back, working to improve circumstances, and contributing to our community and beyond, is at the core of what we value.  We hold deep convictions for many causes, so over time we’ll  build a network of organizations that we will partner with and donate to, the first of which is The Posse Foundation.  We selected The Posse Foundation because of their work with young people of diverse backgrounds, training them to be the strong leaders of tomorrow – the ones who will transform communities, our country and the world. Five percentage of Antedotum’s profits will be given to The Posse Foundation.

Our Founder

Our founder, Karina Perez Marconi,  was raised on the island of Puerto Rico (born to a Cuban dad and Puerto Rican mom), which meant consistent sun exposure at a very early age and accumulative sun damage for the Latina’s olive skin that was already prone to discoloration.  For decades, Karina was plagued by dark spots which were compounded by lingering, post-partum melasma after the birth of her daughter, Havana.  Working for many years in beauty at Chanel’s New York headquarters deepened her understanding of premium skincare, but finding an antidote to her skin aliments remained elusive.  When the family relocated to Aspen, Colorado, the unforgiving mountain climate - dry air, high altitude, wind, sun, cold - only intensified her skin conditions. 

With Colorado being the birthplace of the American cannabis culture, CBD was plentiful and prominent and Karina, curious about its purported curative abiliites, started to sample an assortment of oils and balms.  None of them smelled or looked great, but to her surprise her skin started to transform. This unexpected discovery sent her down an Alice in Wonderland research hole into the alternative CBD skincare universe. What emerged was Antedotum. Having found the one ingredient that is multi-correctional in every way, Karina wanted to share how CBD helped her achieve remarkable results in the look and feel of her skin.

Written by Svn Space

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